Areas of Specialization • Capillary Electrophoresis / Microchip capillary Electrophoresis
• Electrochemical Detection
• Interaction of Enzymes with Carbon Nanotubes
Microchips are one of the most promising analytical platforms due to the great advantages with respect to conventional bench-top equipment. Microfluidic devices are able to offer custom design, high throughput, sensitivity, selectivity and portability. In order to achieve a real point-of-care measurement device, simple instrumentation has to be integrated to drive the injection and separation. Electrochemical detection (ECD) methods have been widely applied for the detection of bio-compounds because they are less susceptible to decreases in signal magnitude during miniaturization and are already portable and inexpensive. For these reasons, we are very interested in studying the design, operation and biological applications of microchips and capillary electrophoresis. In addition, we are also interested in the rational design of biosensors.
Selected Publications
Nanomolar Detection of Glutamate at a Biosensor Based on Screen-Printed Electrodes Modified with Carbon Nanotubes
Raju Khan, Waldemar Gorski and C. D. Garcia
Electroanalysis 23 (2011)2357 – 2363.
Adsorption of Proteins to Thin-Films of PDMS and Its Effect on the Adhesion of Human Endothelial Cells
K. Y. Chumbimuni-Torres, R. E. Coronado, A. M. Mfuh, C. Castro, M. F. Silva, G. R. Negrete, R. Bizios and C. D. Garcia
RSC Advances 4 (2011) 706 - 714
Recent Applications of Carbon-Based Nanomaterials to Analytical Chemistry: A Critical Review Karen Scida, Patricia W. Stege, Gabrielle Haby, German A. Messina, and Carlos D. Garcia
Analytica Chimica Acta 691 (2011) 6-17.
Staining Proteins: A Simple Method to Increase the Sensitivity of Ellipsometric Measurements in Adsorption Studies M. Reza Nejadnik and Carlos D. Garcia
Colloids and Surfaces B: Biointerfaces 82 (2011) 253–257.
Adsorption Kinetics of Catalase to Thin-Films of Carbon Nanotubes Jessica Felhofer, Jonathan Caranto, and Carlos D. Garcia
Langmuir 26 (2010) 17178–17183.
Determination of a Setup Correction Function to Obtain Adsorption Kinetic Data at Stagnation Point Flow Conditions Maria F Mora, Reza Nejadnik, Javier Baylon-Cardiel, Carla E Giacomelli, Carlos D. Garcia
Journal of Colloids and Interface Science 346 (2010) 208 – 215.
Electrostatic and Hydrophobic Interactions Involved in CNT Biofunctionalization with Short ss-DNA Carot, Maria; Torresi, Roberto; Garcia, Carlos; Esplandiu, María José; Giacomelli, Carla
Journal of Physical Chemistry 114 (2010) 4459–4465.
Interaction of D-Amino Acid Oxidase with Carbon Nanotubes: Implications in the Design of Biosensors Maria F. Mora, Carla Giacomelli and Carlos D. Garcia
Analytical Chemistry 81 (2009) 1016 – 1022.
Lab-on-a-Robot: Integrated Microchip – Capillary Electrophoresis, Power Supply, Electrochemical Detector, Wireless Unit, and Mobile Platform C. Berg, D. C. Valdez, P. Bergeron, M. F. Mora, C. D. Garcia and A. Ayon
Electrophoresis 29 (2008) 4914 – 4921.
Electrophoretic Separation of Environmentally Important Phenolic Compounds Using Montmorillonite-Coated Fused Silica Maria F. Mora and Carlos D. Garcia
Electrophoresis 28 (2007) 1197 – 1203.
Faculty
Research Interests 
