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Biomedical Engineering (BME) Course Descriptions

Department of Biomedical Engineering, College of Engineering


BME 1002  Introduction to Biomedical Engineering
(2-0) 2 hours credit. Prerequisites: A grade of “C-” or better in BIO 1404, CHE 1103, and MAT 1214, and concurrent enrollment in CHE 1113, MAT 1224, PHY 1943, and PHY 1951.
This course is an introduction to the interdisciplinary field of biomedical engineering. Topics covered include core biomedical engineering areas such as Biomechanics, Biomaterials and Bioimaging.

BME 2103  Physiology for Biomedical Engineering
(3-1) 3 hours credit. Prerequisites: Major in Biomedical Engineering and a grade of “C-” or better in BME 1002 and CHE 1113.
Fundamental principles of general and organs systems physiology, including composition and concentration of cellular and other body fluids, types of transport (e.g., diffusion, membrane transporters), energy (thermodynamics, metabolism), enzymes, feedback control, and membrane potentials with engineering applications and mathematical modeling. This course includes a 3 hour lecture and a 1 hour recitation.

BME 2114  Cellular Biology for Biomedical Engineering
(3-4) 4 hours credit. Prerequisites: Major in Biomedical Engineering and a grade of “C-” or better in BME 2103 and CHE 1113.
Introduction to cell structure and function, energy conversions, protein sorting, signaling, cytoskeleton, cell adhesion, cell cycle, and mammalian genetics. A laboratory component will focus on techniques and procedures commonly used in cell and molecular biology with bioengineering applications. This class includes a 3 hour lecture and a 4 hour laboratory.

BME 2203  Biomechanics I
(3-1) 3 hours credit. Prerequisites: A grade of “C-” or better in EGR 2323 and PHY 1963, and concurrent enrollment in BME 2114 and BME 2211.
Introduction to the fundamental engineering mechanics with focus on the human body. This course includes a 3 hour lecture and a 1 hour recitation.

BME 2211  Biomedical Engineering Laboratory I
(0-4) 1 hour credit. Prerequisites: A grade of “C-” or better in EGR 2323, PHY 1963, and STA 1403, and concurrent enrollment in BME 2203 and BME 2403.
A biomedical engineering lab in biomechanics and biomaterials. This lab-based course will emphasize on the synthesis and characterization of mechanical properties as well as physical and chemical properties of biomaterials.

BME 2403  Biomaterials I
(3-1) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2103 and EGR 2323 and concurrent enrollment in BME 2114 and BME 2211.
Introduction to the fundamental science of natural and synthetic biomaterials used for repairing human tissues and organs. Topics include crystal structures, phase diagrams, and properties of materials. This course includes a 3 hour lecture and a 1 hour recitation.

BME 3013  Clinical Internship in Biomedical Engineering
(3-0) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2114, BME 2203, and BME 2403.
This course will introduce students to the clinical environment, interacting with clinicians on current clinical problems and engineering approaches.

BME 3022  Biomedical Engineering Technology and Product Development
(2-0) 2 hours credit. Prerequisite: A grade of “C-” or better in BME 3013.
This course will introduce students to current biomedical technologies and product development. (Formerly BME 3023. Credit cannot be earned for both BME 3022 and BME 3023.)

BME 3033  Biomedical Engineering Internship
3 hours credit. Prerequisite: A grade of “C-” or better in BME 3022.
Internship with a biomedical industry. May be repeated for credit but no more than 3 semester credit hours will apply to a bachelor’s degree.

BME 3041-3  Biomedical Engineering Research
1, 2, or 3 hours credit. Prerequisite: Consent of instructor.
Advanced laboratory practice and introduction to biomedical engineering research. This course may be counted as one of the courses to satisfy one of the BME tracks. May be repeated for credit but no more than 3 semester credit hours will apply towards a bachelor’s degree in Biomedical Engineering.

BME 3203  Biomechanics II: Cardiovascular
(3-0) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2203 and BME 2211.
Continuation of fundamental biomechanics to include elasticity, viscoelasticity, deformation, stress analysis, blood flow in the systemic and pulmonary circulation, and fluid-structure interaction.

BME 3303  Bioinstrumentation
(3-1) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2114, BME 2203, EGR 2323, and PHY 1923, and concurrent enrollment in BME 3311.
Fundamental principles of bioinstrumentation used in clinical and research measurements will be covered. Topics include: principles of transducer operation, amplifiers and signal processing, recording and display. This course includes a 3 hour lecture and a 1 hour recitation.

BME 3311  Biomedical Engineering Laboratory II
(0-4) 1 hour credit. Prerequisites: A grade of “C-” or better in BME 2114, BME 2211, and STA 1403, and concurrent enrollment in BME 3303.
A biomedical engineering lab in bioinstrumentation. This course will involve the design and testing of hardware and software for acquiring and analyzing biological signals.

BME 3403  Biomaterials II
(1-5) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2211 and BME 2403.
This course will emphasize materials used in medical applications, including modifications and characterization techniques. This course includes a 1 hour lecture and a 5 hour laboratory.

BME 3413  Biocompatibility of Materials: Tissue-Biomaterial Interaction
(3-0) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2211 and BME 2403.
This course is an introduction to biocompatibility with special emphasis on the interaction of cells and tissues with biomaterials. Blood composition and blood-material interactions, responses of the inflammatory and immune systems to biomaterials, the process of wound healing, protein structure and interactions with material surfaces, and the mechanisms of cell interactions with extracellular matrix components as well as cell/tissue responses to implant materials are reviewed in detail. Case studies of cardiovascular and orthopaedic implants are discussed to illustrate that selection of biocompatible materials is a key aspect of implant design and a crucial choice for the success of various biomedical applications (e.g., tissue engineering and biotechnology) which require regeneration of tissues.

BME 3503  Nanomaterials and Nanobiotechnology
(3-0) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2211 and BME 2403.
This course will introduce an overview of nanomaterials and nanotechnology development. Topics may include biocompatible nanomaterials, microfabrication, microfluidics, lab-on-a-chip, and applications in biomedical engineering. (Formerly titled “Fundamentals of Nanobiotechnology.”)

BME 3703  Biotransport Phenomena
(3-1) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 2114, BME 3303, EGR 2323 and PHY 1923, and concurrent enrollment in BME 3711.
This course introduces the concepts of quantitative modeling of biological systems with respect to mass, momentum and energy transport. We will study the use of conservation laws to model cardiopulmonary, renal, and thermal systems of the human physiology, and also apply these principles to design artificial and extracorporeal devices, drug delivery systems for pharmacokinetic analysis. This course includes a 3 hour lecture and a 1 hour recitation.

BME 3711  Biomedical Engineering Laboratory III
(0-4) 1 hour credit. Prerequisites: A grade of “C-” or better in BME 2114, BME 3303, and STA 1403, and concurrent enrollment in BME 3703.
A biomedical engineering lab in biotransport phenomena. Experiments related to mass, momentum, and energy conservation in biological systems such as measurements of apparent viscosity in microcirculation, oxygen diffusivity and thermal conductivity.

BME 4203  Biomechanics III
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 3203.
Topics may include elasticity, viscoelasticity, deformation, stress analysis, strain measurement, and stress and strain in organs. Tissues covered may include heart, blood vessels, cartilage, and bone.

BME 4213  Tissue Mechanics
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 2203.
Topics may include biomechanics characterization, modeling, and properties of regenerating tissues ranging from bone, cartilage, tendons, ligaments, skin, adipose tissue, nerves, bladder, eye, and pulmonary and cardiovascular tissues.

BME 4293  Topics in Biomechanics
(3-0) 3 hours credit. Prerequisites: Senior status with a major in Biomedical Engineering and a grade of “C-” or better in BME 3203.
Specific topics in biomechanics. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor’s degree.

BME 4403  Molecular Techniques for Cell-Biomaterials Interactions
(2-4) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 2403.
Advanced molecular techniques for characterizing cell-­biomaterials interactions will be taught. Current understanding of topics in cell receptors and signaling mechanisms with application for biomaterial design will be emphasized. Topics will include receptor-ligand communication, methods of identification and quantification, and pathways involved for cell to material stress response. This course includes a 2 hour lecture and a 4 hour laboratory.

BME 4423  Tissue Engineering
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 2403.
This course is an introduction to the current status of, practice, and advances in tissue engineering, the biomedical engineering discipline that applies science and technology to develop replacements for damaged and/or diseased tissues of the body. The course focuses on fundamental aspects of new tissue formation, specifically, cells, biomaterials, biochemical and biophysical stimuli. Applications in bone, cartilage, skin, and vascular tissues are reviewed in detail. Strategies which are used to address current challenges, pursue emerging opportunities and explore new directions are discussed.

BME 4483  Topics in Biomaterials
(3-0) 3 hours credit. Prerequisites: Senior status with a major in Biomedical Engineering and a grade of “C-” or better in BME 3403.
Specific topics in biomaterials. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor’s degree.

BME 4493  Topics in Tissue Engineering
(3-0) 3 hours credit. Prerequisites: Senior status with a major in Biomedical Engineering and a grade of “C-” or better in BME 4423.
Specific topics in tissue engineering. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor’s degree.

BME 4503  Biosensors
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 3503.
Basics to biological detection and in-depth view of device design and performance analyses. Topics may include optical, electrochemical, acoustic, piezoelectric, and nanobiosensors.

BME 4603  Biophotonics
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 3303.
This course will introduce the fundamental principles of biophotonics and will focus on their applications to address critical issues in the frontier of biomedical science and technology. Topics may include fundamentals of light interactions with molecules, cells, and tissues, optical imaging, optical biosensing, flow cytometry, photodynamic therapy, laser tweezers and laser surgery, and nanobiotechnology.

BME 4613  Biomedical Imaging
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 4603.
This course will examine, from a systems perspective, the techniques used in a variety of medical imaging modalities, which include x-ray imaging, computed tomography, magnetic resonance imaging, nuclear medicine, ultrasound imaging, and photoacoustic imaging. The fundamental principles and engineering underlying each imaging modality will be discussed and a performance analysis of each system will be examined.

BME 4623  Biomedical Optics
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 3303.
This course will introduce the fundamental principles of modern and classical optics and their applications for biomedical research. State-of-the-art topics on cutting-edge research in the area of optics and lasers in medicine and biology will be covered.

BME 4703  Biomedical Engineering Thermodynamics
(3-1) 3 hours credit. Prerequisites: A grade of “C-” or better in BME 3703 and EGR 2323.
This course is introduces the basics of engineering thermodynamics and applications in biomedical engineering. The course covers first and second laws, properties of pure substances and mixtures, phase rule, phase and chemical equilibria, and an introduction to statistical thermodynamics. This course includes a 3 hour lecture and a 1 hour recitation.

BME 4713  Cellular Engineering
(3-0) 3 hours credit. Prerequisite: A grade of “C-” or better in BME 3703.
This course focuses on using engineering skills and principles in the analysis and design of cellular functions. The emphasis will be on protein biochemistry, cell metabolism, signaling and adhesion.

BME 4793  Topics in Cellular Engineering
(3-0) 3 hours credit. Prerequisites: Senior status with a major in Biomedical Engineering and a grade of “C-” or better in BME 4713.
Specific topics in cellular engineering. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor’s degree.

BME 4803  Fundamental Computational Bioengineering
(3-0) 3 hours credit. Prerequisites: Major in Biomedical Engineering and a grade of “C-” or better in BME 2114 and EGR 2323.
This course will include fundamental knowledge and skills of mathematical modeling, computer simulation and visualization, with applications in biomedical engineering.

BME 4903  Senior BME Design I
(3-0) 3 hours credit. Prerequisites: Senior status with a major in Biomedical Engineering and a grade of “C-” or better in BME 3023 and STA 1403.
Development of project proposals and presentation of conceptual designs. Industrial collaboration and/or faculty sponsorship of these projects is encouraged.

BME 4913  Senior BME Design II
(3-0) 3 hours credit. Prerequisites: Senior status with a major in Biomedical Engineering and a grade of “C-” or better in BME 4903.
Continuation of the development of an instructor-approved design project, testing of the design project, and presentation of the findings. Industrial cooperation or faculty sponsorship of projects is encouraged.

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